Zanaflex - Muscle Relaxant
Zanaflex - Description
Zanaflex is a treatment indicated for the management of increased muscle tone associated with spasticity, a condition affecting the central nervous system (CNS) causing muscle stiffness and rigidity. Spasticity can occur as a result of many CNS disorders, particularly multiple sclerosis and spinal cord injury. In 1996 the Elan Corporation, plc announced that its wholly-owned subsidiary, Athena Neurosciences, Inc. (Athena), received approval from the U.S. Food and Drug Administration FDA to market Zanaflex (tizanidine hydrochloride), the first new oral treatment for muscle spasticity in the U.S. in
more than 20 years.
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Zanaflex Info
Spasticity is an abnormal increase in involuntary muscle tone caused by damage to the CNS and is characterized by painful muscle spasms as well as muscle stiffness and rigidity. Advanced spasticity, in the worst cases, can leave patients bed-ridden and unable to move without assistance.
In double-blind, placebo-controlled clinical studies, Zanaflex was shown to provide significant relief of spasticity symptoms without causing muscle weakness, which can leave patients unable to perform normal daily activities. Additionally, reported side effects did not include evidence of withdrawal effects. Both weakness and potential withdrawal effects can be characteristic of certain currently approved treatment regimens.
ZANAFLEX - IMPORTANT INFORMATION
Use caution when driving, operating machinery, or performing other hazardous activities. Zanaflex muscle relaxer may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities. • Dizziness is most likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use caution with alcohol, other muscle relaxants, sleep or anxiety medicines, and pain medicines. These drugs may increase drowsiness and dizziness while you are taking Zanaflex muscle
relaxer . Do not take any other medicine during treatment with Zanaflex muscle relaxer without first talking to your doctor or pharmacist.
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BEFORE USING ZANAFLEX MUSCLE RELAXER
Before taking Zanaflex muscle relaxer , tell your doctor if you · have liver disease, · have kidney disease, · have low blood pressure or are on medication to treat high blood pressure; or · are taking birth control pills. • You may not be able to take Zanaflex muscle relaxer, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. Zanaflex muscle relaxer is in the FDA pregnancy C. This means that it is not known whether Zanaflex muscle relaxer will harm an unborn baby. Do not
take this medication without first talking to your doctor if you are pregnant. It is not known whether Zanaflex muscle relaxer passes into breast milk. Do not take Zanaflex muscle relaxer without first talking to your doctor if you are breast-feeding a baby.
HOW TO USE ZANAFLEX MUSCLE RELAXER
Take Zanaflex muscle relaxant exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. Zanaflex muscle relaxer is usually taken several times a day. Follow your doctor's instructions. • Do not take more than three doses of Zanaflex muscle relaxer --or more than 36 mg--in 24 hours. Too much of this medication can damage your liver. Store Zanaflex muscle relaxer at room temperature away from moisture and heat.
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SIDE EFFECTS OF ZANAFLEX MUSCLE RELAXER
If you experience any of the following serious side effects, stop taking Zanaflex muscle relaxer and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · hallucinations or abnormal behavior; or · liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue). Other, less serious side effects may be more likely to occur. Continue to take Zanaflex muscle relaxant and talk to
your doctor if you experience · drowsiness or dizziness; · weakness; · dry mouth; · increased muscle tone or spasms; or · sweating. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
ZANAFLEX MUSCLE RELAXER - DRUG INTERACTIONS
Zanaflex muscle relaxer may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves. Birth control pills can increase the effects of Zanaflex muscle relaxer . Tell your doctor if you are taking birth control pills before starting treatment with Zanaflex muscle relaxer . Zanaflex
muscle relaxant may lower blood pressure. Tell your doctor if you are taking another medicine to lower blood pressure or a medicine to treat another heart condition. Drugs other than those listed here may also interact with Zanaflex . Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
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